Preheat your oven to 350°F (175°C). Line a muffin tin with 6 cupcake liners.
In a small bowl, whisk together the flour, cocoa powder, baking powder, baking soda, and salt. Set aside.
⅔ cup all-purpose flour, 1 tablespoon cocoa powder, ⅛ teaspoon baking powder, ¼ teaspoon baking soda, ¼ teaspoon salt
In a separate bowl, beat together the sugar, buttermilk, oil, vanilla extract, white vinegar, and egg until combined.
¼ cup granulated sugar, ¼ cup buttermilk, 2 tablespoons neutral oil, 1 teaspoon vanilla extract, ½ teaspoon white vinegar, 1 teaspoon red food coloring, 1 egg
Pour the wet ingredients over the dry, Mix until just combined as over mixing will cause the cupcakes to be less tender.
Divide the batter evenly among the cupcake liners, filling each about ⅔ full. Bake in the preheated oven for 14 minutes or until a toothpick inserted in the center comes out clean.
Allow the cupcakes to cool in the tin for 5 minutes before transferring them to a wire rack to cool completely.